先后主持国家基金3项、浙江省重点基金1项、转基因重大专项课题1项、973计划项目骨干成员、十三五重点研发课题骨干、浙江大学“985工程”一流农学学科项目以及中国博士后科学基金等;作为第一作者或通讯作者发表SCI论文30余篇,成果先后发表到Autophagy (IF5=16.586),Nature Communications (IF5=15.804),Obesity Review (IF5=12.125),EMBO Reports (IF5=10.715),Cell Death & Disease (IF5=8.713)等多个权威杂志;作为主要参与者获得浙江省自然科学一等奖1项、浙江省科技进步一等奖1项、神农中华农业科技奖1项、教育部科技进步二等奖1项、重要社会力量奖大北农科技成果二等奖1项,申请国家专利12项,授权9项;并担任Review Editor for Frontiers in Cell and Developmental Biology, Review Editor for Frontiers in Endocrinology,以及Advanced Science,Obesity Review,Nature Communications等国际杂志审稿专家;
教育与工作经历 2020.1-至今:浙江大学动物科学学院,教授 2015.05-2016.08: University of Chicago,留学访问 2011.11-2012.12:Norway Nofima Institute,留学访问 2011.12- 2019.12:浙江大学动物科学学院,副教授 2009.01-2011.05:浙江大学动物科学学院,博士后 2001.09-2004.07:中国海洋大学,博士
担任International journal of Obesity, Plos one, Aquaculture, Asian-australasian Journal of Animal Sciences (AJAS), Animal Genetics, Molecular Genetics and Genomics (MGAG), American Journal of Physiology - Endocrinology and Metabolism (AJP-ENDO),Acta Agri Scand A Animal Sci等国际杂志审稿专家。
身份资质
国家生猪产业技术创新战略联盟 常务理事
浙江省畜牧兽医学会副秘书长
中国畜牧杂志审稿专家
动物营养学报审稿专家
浙江省杰青、重点基金、公益项目等评审专家
先后主持国家基金3项、浙江省重点基金1项、转基因重大专项课题1项、973计划项目骨干成员、十三五重点研发课题骨干、浙江大学“985工程”一流农学学科项目以及中国博士后科学基金等;作为第一作者或通讯作者发表SCI论文30余篇,成果先后发表到Autophagy (IF5=16.586),Nature Communications (IF5=15.804),Obesity Review (IF5=12.125),EMBO Reports (IF5=10.715),Cell Death & Disease (IF5=8.713)等多个权威杂志;作为主要参与者获得浙江省自然科学一等奖1项、浙江省科技进步一等奖1项、神农中华农业科技奖1项、教育部科技进步二等奖1项、重要社会力量奖大北农科技成果二等奖1项,申请国家专利12项,授权9项;并担任Review Editor for Frontiers in Cell and Developmental Biology, Review Editor for Frontiers in Endocrinology,以及Advanced Science,Obesity Review,Nature Communications等国际杂志审稿专家;
教育与工作经历
2020.1-至今:浙江大学动物科学学院,教授
2015.05-2016.08: University of Chicago,留学访问
2011.11-2012.12:Norway Nofima Institute,留学访问
2011.12- 2019.12:浙江大学动物科学学院,副教授
2009.01-2011.05:浙江大学动物科学学院,博士后
2001.09-2004.07:中国海洋大学,博士
研究领域和兴趣
主要从事“动物分子营养与肉品质表观遗传调控”的基础和应用基础研究。
1. 猪肉品质与动物营养调控:营养素调控的表观遗传标记,猪肉质形成的表观遗传机制,营养素与猪表观遗传网络互作
2. 脂肪代谢/肌肉发育的表观遗传机制:多能干细胞发育(iPS)、脂肪生成、肌肉发育等的表观遗传调控网络
3. 代谢紊乱与肥胖病:肥胖的发生、发育,代谢紊乱综合症等表观遗传机制和营养调控
擅长课题
动物营养与猪肉品质
· 猪肉品质与动物营养调控
· 脂肪代谢/肌肉发育的表观遗传机制
· 代谢紊乱与肥胖病
主讲课程
《饲料卫生学》,本科生课程
《脂肪探秘-认识肥胖与健康》,本科生课程
《肉的科学与动物营养》,研究生课程
《动物营养与饲养学》,研究生课程
奖励
金华猪优良肉质性状关键功能基因挖掘及营养调控机制,排名3/5,浙江省自然科学一等奖,2021
优质猪肉生产的饲料营养关键技术研发及应用,排名6/19,神农中华农业科技一等奖,2021
畜禽抗生素减量和养分减排的新型微生态制剂技术研究与产业化,排名8/13,浙江省科技进步奖一等奖,2018
畜禽饲用抗生素减量的饲料营养关键技术及应用,排名4/14,神农中华农业科技奖一等奖,2017
畜禽抗生素减量和养分减排的饲料营养关键技术研究与产业化,排名7/16,大北农科技成果二等奖,2015
仔猪抗菌肽高效营养调控技术研究及产业化,排名6/11,教育部科技进步奖,二等奖,2012
荣誉及学术兼职
中国畜牧兽医学会动物营养分会理事(2018)
中国生物物理学会代谢生物学分会会员
担任International journal of Obesity, Plos one, Aquaculture, Asian-australasian Journal of Animal Sciences (AJAS), Animal Genetics, Molecular Genetics and Genomics (MGAG), American Journal of Physiology - Endocrinology and Metabolism (AJP-ENDO),Acta Agri Scand A Animal Sci等国际杂志审稿专家。
中国畜牧杂志审稿专家
动物营养学报审稿专家
浙江省杰青、重点基金、公益项目等评审专家
专利
(1) 王新霞 汪以真 江芹 蔡旻 mRNA甲基化高通量检测方法,申请号:201610362981.3
(2) 王新霞 汪以真 蔡旻 江芹 基因mRNA的m6A单碱基鉴定方法,申请号:201610799660.X
(3) 王新霞 汪以真 防治大黄鱼脂肪肝的饲料添加剂,专利号:ZL200910096515.5
(4) 王新霞 汪以真 大黄鱼脂肪细胞体外培养方法,专利号:ZL 201110030738.9
(5) 汪以真 王新霞 江芹 蔡旻 单个基因mRNA甲基化水平检测方法, 申请号CN201510429231.9
(6) 汪以真 栾超 王腾浩 冯杰 杜华华 王新霞 路则庆 杨彩梅 一种丁酸梭菌分泌的抗菌肽及其制备方法和应用,专利号: ZL201410030648.3
(7) 汪以真 王腾浩 栾超 冯杰 刘金松 王新霞 杨彩梅 一种地衣芽孢杆菌分泌的抗菌肽及其制备方法和应用,专利号:ZL201410021906.1
(8) 汪以真 朱琳娜 郭佳 韩菲菲 王新霞 冯杰 小鼠Myogenin基因超表达载体的构建方法及用途,专利号ZL201110202707.7
(9) 王新霞 陈炜 陈雨诗 汪以真 DHA作为饲料添加剂在调控肌纤维类型中的新用途,申请号:202110662660.6
(10) 刘有华 王新霞 FTO基因修饰的猪脂肪干细胞及其构建方法与应用,申请号:202110653510.9
(11) 王新霞 刘禹熙 陈炜 陈雨诗 汪以真 高效分离小鼠肌内纤维-成脂祖细胞的方法,专利号:CN202110681912.X
(12) 王新霞 刘禹熙 陈炜 汪以真 一种减轻小鼠胰岛素耐量实验应激的鼠笼装置,申请号:202121364978.8
更多简介
Xinxia Wang†, Ruifan Wu†, Youhua Liu, Yuanling Zhao, Zhen Bi, Yongxi Yao, Qing Liu, Hailing Shi, Fengqin Wang, Yizhen Wang*. m6A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7. Autophagy (IF5: 16.586), 2020 Jul;16(7):1221-1235.doi: 10.1080/15548627.2019.1659617.
Wei Chen, Yushi Chen, Yuxi Liu, Xinxia Wang*. Autophagy in muscle regeneration: potential therapiesfor myopathies. Journal of Cachexia, Sarcopenia and Muscle (IF5= 12.911),2022,doi::10.1002/jcsm.13000.
Youhua Liu, Ying Yang, Ruifan Wu, Chun-chun Gao, Xing Liao, Xiao Han, Botao Zeng, Chaoqun Huang, Yaojun Luo, Yuxi Liu, Yushi Chen, Wei Chen, Jiaqi Liu, Qin Jiang, Yuanling Zhao, Zhen Bi, Guanqun Guo, Yongxi Yao, Yun Xiang, Xiaojun Zhang, Teresa G. Valencaka, Yizhen Wang and Xinxia Wang* mRNA m5C inhibits adipogenesis and promotes myogenesis by respectively facilitating YBX2 and SMO mRNA export in ALYREF-m5C manners Cellular and Molecular Life Sciences (IF5= 10.02),2022 ACCEPTED
Ruifan Wu†, Yushi Chen†, Youhua Liu, Lenan Zhuang, Wei Chen, Botao Zeng, Xing Liao, Guanqun Guo, Yizhen Wang, Xinxia Wang*. m6A methylation promotes white-to-beige fat transition by facilitating Hif1a translation. EMBO Reports (IF5=10.715), 2021 Sep 27;e52348. doi: 10.15252/embr.202052348.
Yushi Chen, Ruifan Wu, Wei Chen, Youhua Liu, Xing Liao, Botao Zeng, Guanqun Guo, Fangfang Lou,Yun Xiang, Yizhen Wang, Xinxia Wang*. Curcumin prevents obesity by targeting TRAF4-induced ubiquitylation in m6A-dependent manner. EMBO Reports (IF5=10.715), 2021 May 5;22(5):e52146. doi: 10.15252/embr.202052146.
Ruifan Wu, Xinxia Wang*. Epigenetic regulation of adipose tissue expansion and adipogenesis by N6-methyladenosine. Obesity Reviews (IF5=12.125), 2021 Feb;22(2):e13124. doi: 10.1111/obr.13124.
Jianzhao Liu†, Yuanxiang Zhu†, Guan-Zheng Luo†, Xinxia Wang†,Yanan Yue, Xiaona Wang, Xin Zong, Kai Chen, Hang Yin, Ye Fu, Dali Han, Yizhen Wang, Dahua Chen &Chuan He. Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nature Communication (IF5: 15.805), 2016 Oct 7;7:13052. doi: 10.1038/ncomms13052.
Chaoqun Huang, Wei Chen, Xinxia Wang* Studies on the fat mass and obesity-associated (FTO) gene and its impact on obesity-associated diseases (IF5=7.661). Accepted
Wei Chen, Yushi Chen, Ruifan Wu, Guanqun Guo, Youhua Liu, Botao Zeng, Xing Liao, Yizhen Wang, Xinxia Wang*. DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling. BMC Biology (IF5=8.182), 2022 Feb 8;20(1):39. doi: 10.1186/s12915-022-01239-w.
Luoyi Zhu, Xinxia Wang*, Yizhen Wang*. Roles of FAM134B in diseases from the perspectives of organelle membrane morphogenesis and cellular homeostasis. Journal of Cellular Physiology (IF5=5.987), 2021 Oct;236(10):7242-7255. doi: 10.1002/jcp.30377.
Youhua Liu†, Yuanling Zhao†, Ruifan Wu, Yushi Chen, Wei Chen, Yuxi Liu, Yaojun Luo, Chaoqun Huang, Botao Zeng, Xing Liao, Guanqun Guo, Yizhen Wang, Xinxia Wang*. mRNA m5C controls adipogenesis by promoting CDKN1A mRNA export and translation. RNA Biology (IF5: 6.774), 2021 Sep 27;1-11. doi: 10.1080/15476286.2021.1980694.
Bocheng Xu, Jie Fu, Yanxiang Qiao, Jinping Cao, Edward C Deehan, Zhi Li, Mingliang Jin*, Xinxia Wang*, Yizhen Wang*. Higher intake of microbiota-accessible carbohydrates and improved cardiometabolic risk factors: a meta-analysis and umbrella review of dietary management in patients with type 2 diabetes. American Journal of Clinical Nutrition (IF5=8.405), 2021 Jun 1;113(6):1515-1530. doi: 10.1093/ajcn/nqaa435.
Marta Bou*†, Xinxia Wang†, Marijana Todorčević, Tone-Kari Knutsdatter Østbye, Jacob Torgersen, Bente Ruyter. Lipid Deposition and Mobilisation in Atlantic Salmon Adipocytes. International journal of molecular sciences (IF5=6.132), 2020 Mar 27;21(7):2332. doi: 10.3390/ijms21072332.
Qing Liu, Yuanling Zhao, Ruifan Wu, Qin Jiang, Min Cai, Zhen Bi, Youhua Liu, Yongxi Yao, Jie Feng, Yizhen Wang and Xinxia Wang*. ZFP217 regulates adipogenesis by controlling mitotic clonal expansion in a METTL3-m6A dependent manner. RNA Biology (IF5: 6.774), 2019 Dec;16(12):1785-1793. doi: 10.1080/15476286.2019.1658508.
Heyuan Liu, Lixia Kai, Huahua Du, Xinxia Wang*, Yizhen Wang*. LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages. Cells (IF5=6.663), 2019 Dec 12;8(12):1626. doi: 10.3390/cells8121626.
Ruifan Wu, Guanquan Guo, Zhen Bi, Youhua Liu, Yuanling Zhao, Nana Chen, Fengqin Wang, Yizhen Wang, Xinxia Wang*. m6A methylation modulates adipogenesis through JAK2-STAT3-C/EBPβ signaling. BBA-Gene Regulatory Mechanisms (IF5: 5.318). 2019 Aug;1862(8):796-806. doi: 10.1016/j.bbagrm.2019.06.008.
Yongxi Yao, Zhen Bi, Ruifan Wu, Yuanling Zhao, Youhua Liu, Qing Liu, Yizhen Wang, Xinxia Wang*. METTL3 inhibits BMSCs adipogenic differentiation by targeting the JAK1/STAT5/C/EBPβ pathway via an m6A-YTHDF2-dependent manner. FASEB Journal (IF5: 5.955). 2019 Jun;33(6):7529-7544. doi: 10.1096/fj.201802644R.
Ruifan Wu, Youhua Liu, Yuanling Zhao, Zhen Bi, Yongxi Yao, Qing Liu, Fengqin Wang, Yizhen Wang, Xinxia Wang*. m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner. Cell Death & Disease (IF5: 8.713), 2019 Feb 20;10(3):171. doi: 10.1038/s41419-019-1417-4.
Qin Jiang, Baofa Sun, Qing Liu, Min Cai, Ruifan Wu, Fengqin Wang, Yongxi Yao, Yizhen Wang, Xinxia Wang*. MTCH2 promotes adipogenesis in intramuscular preadipocytes via a m6A-YTHDF1-dependent mechanism, 2019, FASEB Journal (IF5: 5.955), 2019, 33(2):2971-2981. doi: 10.1096/fj.201801393RRR.
Zhen Bi, Youhua Liu, Yuanling Zhao, Yongxi Yao, Ruifan Wu, Qing Liu, Yizhen Wang, Xinxia Wang*. A dynamic reversible RNA N6-methyladenosine modification current status and perspectives. Journal of Cellular Physiology (IF5: 5.987), 2019 Jun;234(6):7948-7956. doi: 10.1002/jcp.28014.
Ruifan Wu, Youhua Liu, Yongxi Yao, Yuanling Zhao, Zhen Bi, Qin Jiang, Qing Liu, Min Cai, Fengqin Wang, Yizhen Wang, Xinxia Wang* . FTO regulates adipogenesis by controlling cell cycle progression via m6A-YTHDF2 dependent mechanism. BBA-Molecular and Cell Biology of Lipids (IF5: 6.044), 2018 Oct;1863(10):1323-1330. doi: 10.1016/j.bbalip.2018.08.008.
Xinxia Wang, Baofa Sun, QinJiang, Ruifan Wu, Min Cai, Yongxi Yao, Qing Liu, Hailing Shi, Jie Feng, Yizhen Wang. mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes. International Journal of Obesity (IF5: 5.804), 2018 Nov;42(11):1912-1924. doi: 10.1038/s41366-018-0027-z.
Ruifan Wu, Yongxi Yao, Qin Jiang, Min Cai, Qing Liu, Yizhen Wang, Xinxia Wang*. Epigallocatechin gallate targets FTO and inhibits adipogenesis in an mRNA m6A-YTHDF2 dependent manner. International Journal of Obesity (IF5: 5.804), 2018 Jul;42(7):1378-1388. doi: 10.1038/s41366-018-0082-5.
Botao zeng, Ruifan Wu, Yushi Chen, Wei Chen, Youhua Liu, Xing Liao, Guanqun Guo, Xinxia Wang*. FTO knockout in adipose tissue effectively alleviates hepatic steatosis partially via increasing the secretion of adipocyte-derived IL-6. 2022 Apr 15;818:146224. doi: 10.1016/j.gene.2022.146224.
Yuanling Zhao, Youhua Liu, Ruifan Wu, Zhen Bi, Yongxi Yao, Qing Liu, Yizhen Wang, Xinxia Wang*. Understanding m6A function through uncovering the diversity roles of YTH Domain-containing proteins. Molecular Biotechnology (IF5: 2.303), 2019 Jun;234(6):7948-7956. doi: 10.1002/jcp.28014.
Min Cai, Jin Chen, Caihua Yu, Lingling Xi, Qin Jiang, Yizhen Wang, Xinxia Wang*. FAM134B promotes adipogenesis by increasing vesicular activity in porcine and 3T3-L1 adipocytes. Biological Chemistry (IF5:3.922), 2019 Mar 26;400(4):523-532. doi: 10.1515/hsz-2018-0336.
Caihua Yu, Lingling Xi, Jin Chen, Qin Jiang, Hongbo Yi, Yizhen Wang, Xinxia Wang*. PAM, OLA, and LNA are Diferentially Taken Up and Trafcked Via Diferent Metabolic Pathways in Porcine Adipocytes. Lipids (IF5: 2.417), 2017 Nov;52(11):929-938. doi: 10.1007/s11745-017-4302-x.
Xinxia Wang, Caihua Yu, Jie Feng, Jin Chen, Qin Jiang, Shihuan Kuang, Yizhen Wang. Depot-specific Differences in Fat Mass Expansion in WT and ob/ob Mice. Oncotarget (IF5: 5.312), 2017 Jul 11;8(28):46326-46336. doi: 10.18632/oncotarget.17938.
Ruifan Wu, Denghu Jiang, Yizhen Wang, Xinxia Wang*. N6-Methyladenosine (m6A) Methylation in mRNA with A Dynamic and Reversible Epigenetic Modification. Molecular Biotechnology (IF5: 2.303), 2016 Jul;58(7):450-9. doi: 10.1007/s12033-016-9947-9.
Xinxia Wang, Yizhen Wang. From histone to RNA: role of methylation in signal proteins involved in adipogenesis. Current Protein & Peptide Science (IF5: 3.183), 2017;18(6):589-598. doi: 10.2174/1389203717666160627082444.
Xinxia Wang, Linna Zhu, Jingqing Chen, Yizhen Wang. mRNA m6A methylation downregulates adipogenesis in porcine adipocytes. Biochemical and Biophysical Research Communications (IF5:3.381), 2015 Apr 3;459(2):201-207. doi: 10.1016/j.bbrc.2015.02.048.
Xinxia Wang, Jie Feng, Caihua Yu, Qingwu W. Shen, Yizhen Wang. Alterations in oral [1-14C] 18:1n-9 distribution in lean wild-type and genetically obese (ob/ob) mice. Plos one (IF5: 3.788 ), 2015 Mar 31;10(3):e0122028. doi: 10.1371/journal.pone.0122028.
Ting Chen, Zhongwen Li, Yanyan Zhang, Fu Feng, Xiaobin Wang, Xinxia Wang*,Qingwu W Shen. Muscle-Selective knockout of AMPK 2 does not exacerbate diet-induced obesity probably related to altered myokines expression. Biochemical and Biophysical Research Communications (IF5:3.381), 2015 Mar 13;458(3):449-455. doi: 10.1016/j.bbrc.2015.01.075.
Xinxia Wang, Yongjin Li, ChonglinHou, Yang Gao, Yizhen Wang. Physiological and molecular changes in large yellow croaker (PseudosciaenaCrocea R.) with high-fat diet induced fatty liver disease. Aquaculture Research (IF5: 2.415), 2013 Apr 1; 46: 272–282 . doi.org/10.1111/are.12176
Xinxia Wang, Ming Huang, Yizhen Wang. The effect of Insulin, TNFa and DHA on the proliferation, differentiation and lipolysis of preadipocytes isolated from Large Yellow Croaker (PseudosciaenaCrocea R.). Plos one (IF5: 3.788 ), 2012;7(10):e48069. doi: 10.1371/journal.pone.0048069..
Xinxia Wang,Yongjin Li, Yizhen Wang. Adipose triglyceride lipase (ATGL) clone, expression pattern, and regulation by different lipid sources and lipid levels in large yellow croaker (PseudosciaenaCrocea R.). Marine Biotechnology (IF5: 3.322), 2013 Apr;15(2):197-205. doi: 10.1007/s10126-012-9477-9.
Xinxia Wang, Yong-Jin Li, Chong-Lin Hou, Yang Gao, Yi-Zhen Wang. Influence of different dietary lipid sources on the growth, tissue fatty acid composition, histological changes and peroxisome proliferator-activated receptor γ gene expression in large yellow croaker (PseudosciaenaCrocea R.). Aquaculture Research (IF5: 2.415), 2012 Apr 4: 43, 281–291. doi: org/10.1111/j.1365-2109.2011.02826.x.
Xinxia Wang, Zeqing Lu, Linna Zhu, Yanfang Zhang, Yang Ren, Yizhen Wang. Immune responses and gene expression in red swamp crayfish (Procambarus clarkia (Girard)), induced by selenium-enriched exopolysaccharide (Se-ECZ-EPS) produced by bacterium Enterobacter cloacae Z0206. Aquaculture Research (IF5: 2.415), 2010;41:e819-e827. doi: org/10.1111/j.1365-2109.2010.02602.x.
Xinxia Wang, Chengzhen Qi. Effect of dose and feeding frequency in administration of glucan as immunostimulant to Chinese shrimp larvae Fenneropenaeuschinensis from zoea to postlarvae. Journal of Applied Animal Research (IF5: 1.727), 2010;38:123-128. doi:org/10.1080/09712119.2010.9707170
Xiaobin Wang,Qingwu W. Shen,Jie Wang,Zhiguo Zhang,Fu Feng,Ting Chen,Yanyan Zhang,Huan Wei, Zhongwen Li, Xinxia Wang, Yizhen Wang. KLF7 Regulates Satellite Cell Quiescence in Response to Extracellular Signaling. Stem Cells (IF5: 6.841), 2016 May;34(5):1310-20. doi: 10.1002/stem.2346.
Jingqing Chen, Xihong Zhou, Weiche Wu, Xinxia Wang, Yizhen Wang. FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice. J Physiol Biochem (IF5: 3.617), 2015 Sep;71(3):405-13. doi: 10.1007/s13105-015-0420-1.
Xihong Zhou, Weiche Wu, Jingqing Chen, Xinxia Wang,Yizhen Wang. AMP-activated protein kinase is required for the anti-adipogenic effects of alpha-linolenic acid. Nutrition & Metabolism (IF5: 5.022), 2015 Mar 8;12:10. doi: 10.1186/s12986-015-0006-5.
Xihong Zhou, Jingjing Chen, Weiche Wu, Xinxia Wang, Yizhen Wang. Role of adenosine 5'-monophosphate-activated protein kinase in α-linolenic acid-induced intestinal lipid metabolism. British Journal of Nutrition (IF5: 4.816), 2015 Sep 28;114(6):866-72. doi: 10.1017/S0007114515002391.
Xihong Zhou, Jingqing Chen, Jin Chen, Weiche Wu, Xinxia Wang, Yizhen Wang. The beneficial effects of betaine on dysfunctional adipose tissue and N6-methyladenosine mRNA methylation requires the AMP-activated protein kinase α1 subunit. The Journal of Nutritional Biochemistry (IF5: 6.114), 2015 Dec;26(12):1678-84. doi: 10.1016/j.jnutbio.2015.08.014.
Xihong Zhou, Fenqing Wang, Hangxian Yang, Jingqing Chen, Yang Ren, Zhangqin Yuan, Xinxia Wang,Yizhen Wang. Selenium-enriched exopolysaccharides produced by Enterobacter cloacae Z0206 alleviate adipose infammation in diabetic KKAy mice through the AMPK/SirT1 pathway. Molecular Medicine Reports (IF5: 2.754), 2014 Feb;9(2):683-8. doi: 10.3892r.2013.1859.
Xihong Zhou, Jingqing Chen, Fenqing Wang, Hangxian Yang, Xinxia Wang, Yizhen Wang. Selenium-enriched exopolysaccharides produced by Enterobacter cloacae Z0206 improve muscle glucose uptake of diabetic KKAy mice via AMPK pathway. Journal of Physiology and Biochemistry (IF5: 3.617), 2014 Jun;70(2):547-54. doi: 10.1007/s13105-014-0334-3.
Yang Ren, Jing Huang, Xiufeng Yu, Tizhong Shan1, Xihong Zhou, Xinxia Wang, Yizhen Wang. Breed difference of porcine Sirtuin 1, adipose triglyceride lipase (ATGL) and hormone sensitive lipase (HSL). Livestock science (IF5: 2.252), 2010 Dec;88(12):3909-17. doi: 10.2527/jas.2010-2880.
学术论文(中文)
廖星,陈炜,刘有华, 王新霞. 胡椒碱的生物学功能及其在畜禽生产中的应用研究进展[J].动物营养学报,2022(接收).
陈炜,陈雨诗,刘禹熙,王新霞. 自噬对再生中肌肉干细胞的作用[J].中国细胞生物学学报,2021(接收).
陈炜,刘佳琪,刘禹熙,王新霞. 棕色脂肪组织内分泌功能的最新研究进展[J] 中国细胞生物学学报,2022(接收).
姚永曦,吴睿帆,汪以真,王新霞. 腺病毒与慢病毒感染猪原代细胞的比较研究[J].中国畜牧杂志,2018,54(04):83-88.
席玲玲,蔡日,王新霞,汪以真. 不同脂肪酸对体外培养猪肌管细胞脂质代谢的影响[J].中国畜牧杂志,2017,53(02):58-64.
蒋登湖,路则庆,吴睿帆,汪以真,王新霞.生猪养殖粪源重金属污染现状及防治措施[J].猪业科学,2016,33(09):95-98.
科研项目
国家自然科学基金区域联合基金(课题主持):金华猪优良肉质性状形成的分子机制及营养调控研究(U21A20249)
国家自然科学基金面上项目(主持):mRNA m6A甲基化修饰在猪脂肪细胞定向分化过程中的功能和机制(31572413)
装备预研教育部联合基金(主持):战场烧伤“仿生-抗炎-快速”修复新技术研究(6141A020226)
国家十三五重点研发(课题骨干主持):日粮组成与饲养体制对畜禽健康优质肉形成的调控及机制(2018YFD0500400)
国家自然科学基金面上项目(主持):FAM134B基因对猪脂肪沉积的影响及其调控机制研究
国家自然科学基金青年基金(主持):甘油三酯脂酶(ATGL)基因表达对脂肪沉积的影响及营养调控的分子机制
浙江省自然科学基金重点项目(主持): 基于mRNA m5C甲基化的猪肌内脂肪沉积关键基因筛选及功能验证(Z22C179564)
浙江省自然科学基金重点项目(主持): m6A结合蛋白YTHDF1调控猪间充质干细胞定向发育为脂肪细胞的作用及机制研究(LZ17C170001)
973计划项目(课题骨干主持):机体碳代谢对猪脂肪沉积和肉品质形成的调控(2012CB124705)
国家转基因重大专项(子课题负责人主持):基于转录后mRNA甲基化修饰水平上的猪肌内脂肪沉积关键基因筛选及其功能鉴定(2014ZX0800949B)
浙江大学“985工程”一流农学学科(主持):猪肉质及抗病性状关键功能基因发掘及其调控
浙江省重点科技创新团队项目:饲料研发与安全
横向课题(参与):生猪养殖安全与肉品质研究
王新霞的视频更多>>
客户评价